Figure 1. Cumulative incidence of major CVD, stratified by parental history of CVD and modifiable risk factors.

Kaplan–Meier cumulative incidence plots for offspring with and without parental history of CVD, stratified by absence or presence of modifiable parental risk factors. Depicted in smoking (A), HTN (B), DM (C), obesity (D), and HCL (E). CVD indicates cardiovascular disease; DM, diabetes mellitus; HCL, hypercholesterolemia; HTN, hypertension; and PHx, parental history.