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. 2023 Mar 9;12(6):e028492. doi: 10.1161/JAHA.122.028492

Table 2.

Trade‐Offs in the Absolute Risk of Various Attributes That Patients Would be Willing to Accept Relative to a 1% Decrease in Risk of Death Within 1 Year from a Discrete Choice Experiment Examining Preferences of Patients With Chronic Kidney Disease for Invasive Versus Conservative Treatment of Acute Coronary Syndrome

Attribute Marginal rate of substitution relative to a 1% decrease in the risk of death, % (95% CI)
Treatment approach (invasive versus conservative) 1.7 (0.0–3.7)
Risk of another heart attack within 1 year 1.4 (0.8–2.0)
Risk of AKI requiring dialysis 1.9 (1.2–2.5)
Risk of ESKD 1.4 (1.0–1.9)

The marginal rate of substitution for the treatment approach indicates that, for patients to accept an invasive over conservative approach, it would have to correspond to a 1.7% or more decrease in the risk of death. For the attributes of risk of recurrent myocardial infarction, risk of AKI, and risk of ESKD, the marginal rate of substitution indicates the absolute percentage increase in the risk of the listed attribute that patients are willing to accept with a choice that achieves a 1% decrease in the risk of death within 1 year. AKI indicates acute kidney injury; and ESKD, end‐stage kidney disease.