Table 3.
Cox Proportional Hazards Regression Analysis of Combined Cohorts (n=596)
| Variable | Hazard ratio | 95% CI | P value |
|---|---|---|---|
| All‐cause mortality model | |||
| Age, y | 1.098 | 1.078 to 1.119 | <0.0001 |
| BMI | 1.037 | 1.009 to 1.064 | 0.0077 |
| Sex, female | 0.9452 | 0.6829 to 1.312 | 0.7348 |
| PNC [≥6 ng/mL] | 1.414 | 1.014 to 1.993 | 0.044 |
| NT‐proBNP [≥300 pg/mL] | 1.22 | 0.8032 to 1.794 | 0.33 |
| High blood pressure | 1.231 | 0.8592 to 1.796 | 0.2676 |
| Heart attack | 0.8792 | 0.5097 to 1.484 | 0.6362 |
| Coronary artery disease | 1.276 | 0.7762 to 2.032 | 0.3205 |
| Heart failure model | |||
| Age, y | 1.008 | 0.9963 to 1.021 | 0.1764 |
| BMI | 1.020 | 1.002 to 1.037 | 0.0232 |
| Sex, female | 1.228 | 0.9586 to 1.578 | 0.1060 |
| PNC [≥6 ng/mL] | 1.555 | 1.213 to 2.002 | 0.0006 |
| NT‐proBNP [≥300 pg/mL] | 0.9395 | 0.6623 to 1.300 | 0.7161 |
| High blood pressure | 1.259 | 0.9639 to 1.655 | 0.0950 |
| Heart attack | 1.663 | 1.092 to 2.516 | 0.0169 |
| Coronary artery disease | 1.353 | 0.9043 to 1.988 | 0.1326 |
Hazard ratios are adjusted for all other predictor variables and representative of all‐cause mortality (top) or development of heart failure (bottom). BMI indicates body mass index; NT‐proBNP, N‐terminal pro‐B‐type natriuretic peptide; and PNC, precursor pro‐N‐cadherin.