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Dose–response of 4-PrO-DMT (0.03–30 mg/kg s.c.) for effects on body temperature and locomotor activity. (A) Dose–response curve and potency for 4-PrO-DMT to change body temperature across the 30 min pre to post session. (B) Dose–response curve and potency for 4-PrO-DMT to decrease distance traveled. * = statistically significant values (p < 0.05) compared to vehicle controls (0 mg/kg). Data represent mean ± SEM for n = 5–6/dose.
