Table 1.
Demographic Table Summarizing the Stable Bronchiectasis Cohort (Overall and by Cluster)
| Demographic | All (N = 57) |
Cluster 1 (n = 31) |
Cluster 2 (n = 26) |
P value (between Clusters) |
|---|---|---|---|---|
| Sex, n (%) | ns | |||
| Female | 45 (78.9) | 25 (80.6) | 20 (76.9) | — |
| Male | 12 (21.1) | 6 (19.4) | 6 (23.1) | — |
| Age, median (IQR) | 63.00 (54.00–72.00) | 65.00 (55.00–75.00) | 62.50 (54.30–69.80) | ns |
| Disease severity (as FACED score) | 2.00 (2.00–4.00) | 3.00 (2.00–4.00) | 2.00 (1.0–3.00) | 0.0376 |
| Radiological severity (as Reiff score) | 4.00 (3.00–8.00) | 6.00 (4.00–8.00) | 4.00 (2.25–5.00) | 0.0063 |
| BMI | 21.00 (19.00–24.80) | 20.20 (19.00–24.20) | 21.6 (19.30–25.80) | ns |
| Number of exacerbations (in the year preceding study recruitment), median (IQR) | 2.00 (1.00–4.00) | 3.00 (2.00–5.00) | 2.00 (1.00–2.75) | 0.0460 |
| Smoking status, n (%) | ns | |||
| Ex-smoker | 23 (40.4) | 11 (35.5) | 12 (46.2) | — |
| Never smoker | 34 (59.6) | 20 (64.5) | 14 (53.8) | — |
| Lung function (as FEV1% predicted), median (IQR) | 71.00 (62.00–90.00) | 71.00 (59.50–88.50) | 76.50 (67.30–90.80) | ns |
| mMRC dyspnoea score, n (%) | ns | |||
| 0 | 24 (42.1) | 12 (38.7) | 12 (46.2) | — |
| 1 | 23 (40.4) | 11 (35.5) | 12 (46.2) | — |
| 2 | 3 (5.3) | 1 (3.2) | 2 (7.7) | — |
| 3 | 6 (10.5) | 6 (19.4) | 0 (0) | — |
| 4 | 1 (1.8) | 1 (3.2) | 0 (0) | — |
| Chronic macrolide use, n (%) | ns | |||
| No | 49 (86.0) | 28 (90.4) | 21 (80.8) | — |
| Yes | 8 (14.0) | 3 (9.7) | 5 (19.2) | — |
| Inhaled corticosteroid use, n (%) | ns | |||
| No | 35 (61.4) | 22 (71.0) | 13 (50.0) | — |
| Yes | 22 (38.6) | 9 (29.0) | 13 (50.0) | — |
| Total number of courses of oral antibiotics in the 3-yr period preceding study recruitment, median (IQR) | 4.00 (2.00–6.00) | 4.00 (2.25–9.00) | 4.00 (2.00–6.00) | ns |
Definition of abbreviations: BMI = body mass index; FACED = FEV1, age, chronic colonization, extension, and dyspnea; IQR = interquartile range; mMRC = modified Medical Research Council dyspnea scale; ns = nonsignificant.
Demographic table illustrating the study cohort with stable bronchiectasis (n = 57) and P values for significant differences observed between clusters. Demographic data are presented as median value (and IQR) and/or patient n (and %), as appropriate. Significant P values (<0.05) are indicated in bold.