. 2022 Nov 30;207(7):899–907. doi: 10.1164/rccm.202203-0580OC

Table 3.

Odds Ratios of Bronchopulmonary Dysplasia-associated Pulmonary Hypertension and Survival by Clinical Covariates

Variable	Crude OR (95% CI)	Adjusted OR^*	95% CI		P Value
Variable	Crude OR (95% CI)	Adjusted OR^*	Lower	Upper	P Value
Analysis between cases and control subjects^*
Birth weight^†	0.62 (0.44–0.87)	1.00	0.48	0.94	0.02
Patent ductus arteriosus	3.22 (1.27–8.19)	3.18	1.13	8.95	0.03
Late-onset sepsis	3.00 (0.95–9.53)	2.39	0.66	8.64	0.18
Fi_O₂ at postnatal Day 28^‡	1.20 (0.99–1.45)	1.01	0.94	1.44	0.17
IH event duration <80%^§	1.22 (1.01–1.47)	1.09	0.87	1.35	0.46
IH event duration <70%^§	1.00 (1.00–1.00)	1.00	0.96	1.03	0.76
Analysis by survival^ǁ
Patent ductus arteriosus	4.17 (0.93–18.62)	6.81	1.09	42.42	0.04
Fi_O₂ at postnatal Day 28^‡	1.03 (1.00–1.06)	NS	—	—	—
IH event duration <70%^§	1.03 (1.00–1.07)	1.22	1.00	1.47	0.04

Definition of abbreviations: CI = confidence interval; IH = intermittent hypoxemia; OR = odds ratio; NS = not significant.

Analyses by logistic regression between cases and control subjects.

^{^†}

For every 100 g change in birth weight.

^{^‡}

For every 10% change in Fi_O₂.

^{^§}

For every second duration of an intermittent hypoxemic event. Separate regression models performed for each IH characteristic.

^{^ǁ}

Analyses by forward stepwise likelihood ratio within cases by outcome of survival.