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Immunizations of mice with FliCD decrease the C. difficile spores and toxins in feces after a challenge with C. difficile spores. The TcdA (A) or TcdB (B) levels in feces were determined via ELISA. (C) R20291 spore concentrations in feces. The data are presented as the mean ± SEM (n = 10) (*, P < 0.05; **, P < 0.01 versus PBS).
