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. 2023 Apr 18;3(4):621–639. doi: 10.1158/2767-9764.CRC-22-0389

TABLE 1.

Overlap of BAZ1A-dependent 1α,25(OH)2D3-regulated gene expression with genes annotated to 1α,25(OH)2D3-regulated NF regions and VDR-binding sites

Cell Cistrome logPval NumberCistromeGenes Threshold MostSignificant
RC43N RC43N.VDR.ATAC 11.35 1,358 Significant PIK3R6
RC43T RC43T.VDR.ATAC 3.01 349 Significant PIK3C2G
RC43T RC43T.VDR.ChIP 1.40 28 Significant FRG2B
HPr1AR HPr1AR.VDR.ATAC 0.82 73 NS KCNH6
LNCaP LNCaP.VDR.ATAC 0.40 80 NS ANGPTL7
RC43N RC43N.VDR.ChIP 0.28 14 NS ANKRD26P1
LNCaP LNCaP.VDR.ChIP 0.26 51 NS POTEM

NOTE: Genes were annotated to ATAC-seq or ChIP-seq regions within 100 kb and those genes overlapped with the DEGs in the same cell background with elevated BAZ1A expression, and enrichment tested with a hypergeometric test (lower.tail = FALSE).