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. 2023 Apr 4;13:1096882. doi: 10.3389/fonc.2023.1096882

Figure 4.

Figure 4

Increasing miR-9 decreases, cell migration, decreases cell proliferation, and increases chemosensitivity in UM-SCC-12 cells. (A) Representative images of cell migration of miR-9 mimic and mock oligo control transfected UM-SCC-12 cells across time points. Transient transfection of miR-9 mimic in UM-SCC-12 cells resulted in significantly decreased (B) cell migration at 24h, 48h, and 72h, (C) and cell proliferation, (D) increased sensitivity to cisplatin at 2.47 μM, 7.41μM and 22.22μM and (E) a lowering of its IC50 to cisplatin compared to mock oligo control. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.