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. 2023 Apr 4;13:1096882. doi: 10.3389/fonc.2023.1096882

Figure 5.

Figure 5

Reducing levels of miR-9 increases cell migration, increases cell proliferation, and decreases chemosensitivity in UM-SCC-10A cells. (A) Representative images of cell migration of miR-9 inhibitor or mock oligo control transfected UM-SCC-10A cells across time points. Transient transfection of miR-9 inhibitor in UM-SCC-10A cells resulted in significantly increased (B) cell migration at 24h, 48h, and 72h, (C) and cell proliferation, (D) decreased sensitivity to cisplatin at 2.47 μM, 7.41μM and 22.22μM and (E) an increase its IC50 to cisplatin compared to mock oligo control. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.