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Minimal clinically important difference (95% confidence interval) in the 6-minute-walk distance using (A) anchor-based (physical component score change of at least five) and (B) distributional methods. 6MWD = 6-minute-walk distance; PHAR = Pulmonary Hypertension Association Registry; ROC = receiver operating characteristic; SMD = standardized mean difference; SRM = standardized response mean.
