Figure 4.

Virally expressed hCD40L induces DC maturation in tumor histocultures: Patient histocultures were treated either with viruses or left uninfected (A). Cells were harvested from histocultures on day 3 for analysis of DC maturation markers. MFI for DC maturation makers CD80 (B), CD83 (C), and CD86 (D) of CD11c⁺ and CD3⁻ populations. Data are presented as mean ± SEM. For each condition, there are triplicate analyses, all of which are shown (*p < 0.05; ***p < 0.001). MFI, mean fluorescence intensity.