Table 2.
Systematic review results relating to neurological manifestations in infants with COVID-19.
| Author | PN | Age/gender | Diagnosis | Initial NS | NE | Fever before NS | LD | EEG | MRI-CT | CSF analysis | SD on CSF | Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dugue R | 1 | 6w/M | Seizures | Seizures | N | yes | A | A | N | NP | N | NA |
| Nathan N | 4 | <3 m/M | Non-specific neurological diagnosis | Axial hypotonia and moaning sounds | NA | yes | NA | NA | NA | N | N | NA |
| McLendon L | 1 | 17 m/F | ADEM | Fatigue, progressively worsening weakness, and unsteady gait | A | yes | A | NP | A | A | NP | IVIG; steroids |
| Vraka K | 1 | 13 m/F | ADEM | Altered consciousness and seizures | A | yes | NA | A | A | A | N | Steroids |
| Garcia-Howard M | 1 | 3 m/F | Seizures | Seizures | A | yes | A | N | N | N | NP | Levetiracetam |
PN: Patient Number; NE: Neurological examination; NS: neurological signs; RS: Respiratory support; LD: Laboratory data; EEG: Electroencephalography; EMG: Electromyography; NCS: Nerve Conduction Study; CSF: Cerebrospinal Fluid; SD: SARS-CoV-2 Detection; NP: Not performed; NA: Not available; A: abnormal; N: normal; ADEM: Acute Disseminated Encephalomyelitis; IVIG: Intravenous immunoglobulins.