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. 2021 Jan 17;30(3-4):245–254. doi: 10.1038/s41434-020-00218-6

Fig. 2. Heptapeptide-modified AAV9 capsids and their transduction efficiencies in HUVECs.

Fig. 2

a Scheme of the heptapeptides (7-mers) inserted at AAV9 capsid site A589 and the incorporated expression cassette consisting in firefly luciferase reporter under the control of the PGK promoter. pA polyA signal, ITR inverted terminal repeats for AAV genome packaging. b Luciferase activity in HUVECs expressed as percentage relative to that of AAV9wt. Cntrl, untransduced HUVECs. Data are reported as mean ± SD from experiments performed in triplicate, ****p < 0.001 (unpaired t-test).