Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Role of MDSCs in hematological malignancies and Hematopoietic stem cell transplantation. MDSCs have a favorable role in that they suppress T cell activity thereby preventing GVHD after HSCT (Left side of figure). In contrast, the unfavorable expansion of MDSCs promotes tumor growth by increasing angiogenesis, creating a pre-metastatic niche, suppressing T-cell activity and recruiting Tregs in the TME (Right side of figure).
