TABLE 2.

Differential metabolite screening results.

Compared groups	Num. of total ident	Num. of total sig	Num. of Sig.Up	Num.of Sig.down
HFD.vs. ND_pos	771	290	167	123
VC.vs. HFD_pos	771	217	101	116
VD.vs. HFD_pos	771	271	161	110
VC_VD.vs. HFD_pos	771	291	182	109
HFD.vs. ND_neg	430	167	106	61
VC.vs. HFD_ neg	430	133	92	41
VD.vs. HFD_ neg	430	164	125	39
VC_VD.vs. HFD_neg	430	176	140	36

The threshold is set to VIP >1.0, FC > 1.2 or FC < 0.833, and p-value < 0.05.

pos, positive polarity mode; neg, negative polarity mode; Num of Total Ident, total number of identification results of metabolites; Num of Total Sig, total number of metabolites with significant difference; Num of Sig Up, total number of metabolites significantly upregulated; Num of Sig down, total number of metabolites significantly downregulated.