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. 2023 Apr 5;13:1053248. doi: 10.3389/fonc.2023.1053248

Table 1.

Demographics, Clinical Characteristics, and OS.

Variable Number Percentage Survival Rate λ2 P-value
1-year 3-year 5-year
Age, years 0.55 0.96
 0 20 6.6 82.6 82.6 82.6
 1—4 55 18.3 89 70.7 70.7
 5—9 26 8.6 79.2 69.3 69.3
 10—14 61 20.3 96.2 75 75
 15—19 139 46.2 94.9 82.5 78.8
Gender 0.46 0.5
 Male 143 47.5 97.2 86.3 81.2
 Female 158 52.5 94.8 87.2 79.2
Race 3.48 0.48
 White 240 79.7 97.5 92.5 86.4
 Black 41 13.6 79.3 65.7 65.7
 AI 2 0.7 50 —— ——
 API 15 5.0 73.3 —— ——
 Unknown 3 1.0 —— —— ——
Primary site 44.5 <0.01
 Upper lobe 81 26.9 94.7 84.2 78.3
 Middle lobe 27 9.0 85 85 85
 Lower lobe 100 33.2 94.9 85.9 84.1
 T and B 40 13.3 88.4 85 85
 Overlapping 16 5.3 54.5 54.5 54.5
 NOS 37 12.3 79.8 26.9 26.9
Laterality 26.2 <0.01
 Left 128 42.5 98.4 86.9 84
 Right 155 51.5 94.2 84.4 76.9
 Bilaterality 14 4.7 70.1 60.1 33.4
 NOS 4 1.32 —— —— ——
Location 60.5 <0.01
 LUL 48 15.9 93.1 87.7 84.8
 LLL 43 14.3 97.5 89.8 89.8
 RUL 31 10.3 92.9 89 89
 RML 27 9.0 88.9 85 85
 RLL 57 18.9 87.4 83.1 83.1
 Trachea 4 1.3 100 100 100
 Bilaterality 7 2.3 57.1 57.1 38.1
 LM 24 8.0 95.8 87.1 87.1
 RM 12 4.0 100 88.9 77.8
 NOS 32 10.6 80.2 45.1 39.4
 overlapping 16 5.3 81.3 54.5 54.5
Histology 110 <0.01
 Carcinoid tumor 89 29.6 97.6 97.6 97.6
 MEC 37 12.3 97.1 97.1 ——
 Adenocarcinoma 31 10.3 78.3 55.4 ——
 SCC 12 4.0 20.8 —— ——
 NET 16 5.3 48.7 —— ——
 Pulmonary blastoma 67 22.3 93.7 77.2 70.5
 Atypical carcinoma 7 2.3 100 —— ——
 other, NOS 42 14.0 84.9 43.4 34.7
Grade 67.2 <0.01
 I 53 17.6 96.2 96.2 ——
 II 30 10.0 76.2 —— ——
 III 18 6.0 36.1 11.3 ——
 IV 10 3.3 77.8 44.4 44.4
 Unknown 190 63.1 97.3 93.3 85.8
Surgery 100 <0.01
 no 59 19.6 89.4 47.2 23.4
 yes 242 80.4 97.5 94.4 90.1
operation methods 111 <0.01
 Local tumor destruction or excision 9 3.0 88.9 76.2 76.2
 sublobar resection 56 18.6 98.2 94.2 89.6
 Bronchial sleeve resection 13 4.3 100 100 100
 lobectomy 120 39.9 96.6 89.8 87.2
Pneumonectomy 21 7.0 75.4 —— ——
 Lobe or bilobectomy extended 16 5.3 100 100 100
 resection NOS 7 2.3 100 40 40
TNM stage 105 <0.01
 I 65 21.6 100 97.9 97.9
 II 20 6.6 100 100 100
 III 24 8.0 59.7 —— ——
 IV 33 11.0 74.6 34.4 13.1
 unknown 159 52.8 97.5 87.1 81.8
Radiotherapy 1.43 0.23
 yes 28 9.3 75 —— ——
 no 273 90.7 97.8 93.2 88
Chemotherapy 108 <0.01
 yes 112 37.2 75.9 51.7 48.1
 no/unknown 189 62.8 98.9 96.9 96.1

AI, American Indian/Alaska Native; API, Asian or Pacific Islander; T and B, Trachea and Main bronchus; Overlapping, Overlapping lesion of lung; LUL, left upper lobe; LLL, left lower lobe; RUL, right upper lobe; RML, right middle lobe; RLL, right lower lobe; LM, left main bronchus; RM, right main bronchus; MEC, mucoepidermoid carcinoma; SCC, squamous cell carcinoma; NET, neuroendocrine tumor.