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. 2023 Apr 5;17:1135227. doi: 10.3389/fncel.2023.1135227

FIGURE 1.

FIGURE 1

EA treatment alleviated the depressive-like behavior produced by PSD. (A) Changes in regional cerebral blood flow (rCBF) during BCCAO operation in mice. (B,C) The neuroglial outcome of each group at 1 day and 3 days after reperfusion. (n = 8, **P < 0.01 vs. the sham group). (D) The treatment of EA reversed the increased immobility in the TST produced by PSD. (E) The expose of PSD significantly increased the immobility time in FST, whereas EA treatment reversed this increase. (F,G) PSD significantly prolonged the latency to feed during the novel environment in NSF test, while EA treatment prevented this increase. Neither PSD nor EA treatment altered the latency to feed in home cage. (H) PSD elicited a significant reduction in the time spent in the central arena of the open field, whereas EA treatment prevented this reduction. (I) The expose of PSD significantly reduced time spent in open arms in EPM test, while EA treatment reversed this decrease.