Table 1.

Qualifying events to determine sepsis time zero

1. Organ dysfunction with chronic conditions removed. Earliest resulted date/time is used if multiple criteria are met
Abnormal lactate: > 2 or intermediate or critical
SBP < 90
MAP < 65
Creatinine > 2 exclude renal failure
Platelet < 100,000
INR > 1.5 excluding patients on warfarin
Vent in place (mechanical vent)
Bilirubin > 2 excluding liver failure
Diagnostic sepsis order sets ordered date/time. Earliest order date/time is used if multiple criteria are met
ED triage completion date/time