Fig. 3.

Analysis of drug sensitivity and differences in biological characteristics in patients with lung adenocarcinoma harboring mutations in TP53. A Difference in drug Sensitivity to LUAD with TP53-MUT and TP53-WT TP53, the horizontal axis is the TP53 mutation grouping, and the vertical axis is the 50% inhibitory concentration (IC50). B The difference of KEGG pathway between TP53-MUT and TP53-WT, the horizontal axis is the KEGG pathway, and the vertical axis is the signaling pathway enrichment score. C The difference of Hallmark between TP53-MUTand TP53-WT, the horizontal axis is hallmark, and the vertical axis is hallmark enrichment score