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. 2023 Apr 3;29:100626. doi: 10.1016/j.lanepe.2023.100626

Table 1.

Percentage of individuals with an existing autism diagnosis as of 31st December 2018 and adjusted rate ratios for sex, age, calendar year, social deprivation, and ID.

Covariate Males
Females
Crude percentage diagnosed autistic (95% CI) Approximate proportion already diagnosed autistic by end of 2018 Adjusted rate ratioa Crude percentage diagnosed autistic (95% CI) Approximate proportion already diagnosed autistic by end of 2018 Adjusted rate ratioa
Sex
 Male 1.22 (1.18–1.26) 1 in 80
 Female 0.35 (0.33–0.38) 1 in 280
Age band
 0–4 years 0.54 (0.40–0.71) 1 in 190 1 0.24 (0.15–0.37) 1 in 420 1
 5–9 years 3.07 (2.83–3.32) 1 in 33 5.36 (4.03–7.13) 0.82 (0.70–0.96) 1 in 120 3.24 (2.07–5.07)
 10–14 years 4.36 (4.08–4.66) 1 in 23 7.42 (5.60–9.85) 1.29 (1.13–1.45) 1 in 80 4.84 (3.12–7.49)
 15–19 years 4.40 (4.09–4.72) 1 in 23 7.05 (5.31–9.36) 1.37 (1.20–1.56) 1 in 75 4.93 (3.18–7.65)
 20–29 years 2.55 (2.38–2.73) 1 in 39 3.91 (2.95–5.19) 0.75 (0.66–0.86) 1 in 130 2.45 (1.58–3.81)
 30–39 years 0.54 (0.46–0.62) 1 in 190 0.90 (0.66–1.23) 0.19 (0.15–0.23) 1 in 550 0.66 (0.41–1.06)
 40–49 years 0.24 (0.20–0.29) 1 in 420 0.43 (0.30–0.59) 0.12 (0.09–0.15) 1 in 850 0.42 (0.26–0.70)
 50–59 years 0.18 (0.15–0.23) 1 in 550 0.32 (0.23–0.46) 0.10 (0.07–0.13) 1 in 1000 0.37 (0.22–0.61)
 60–69 years 0.13 (0.09–0.17) 1 in 800 0.23 (0.15–0.34) 0.03 (0.01–0.05) 1 in 3400 0.11 (0.05–0.24)
 70+ years 0.03 (0.02–0.06) 1 in 3000 0.06 (0.03–0.12) <0.01 (0.00–0.01) <1 in 9500 0.01 (0.00–0.07)
Townsend deprivation quintile
 1 (least) 0.95 (0.88–1.02) 1 in 110 1 0.27 (0.23–0.30) 1 in 380 1
 2 1.12 (1.04–1.21) 1 in 90 1.14 (1.02–1.27) 0.36 (0.32–0.41) 1 in 280 1.33 (1.10–1.61)
 3 1.33 (1.24–1.42) 1 in 75 1.27 (1.14–1.41) 0.38 (0.34–0.43) 1 in 260 1.30 (1.08–1.56)
 4 1.41 (1.31–1.51) 1 in 70 1.25 (1.12–1.40) 0.39 (0.34–0.45) 1 in 260 1.21 (1.00–1.48)
 5 (most) 1.60 (1.47–1.75) 1 in 60 1.43 (1.26–1.62) 0.44 (0.37–0.52) 1 in 220 1.38 (1.10–1.73)
ID diagnosis
 No ID diagnosis 1.05 (1.02–1.09) 1 in 95 1 0.29 (0.27–0.31) 1 in 340 1
 ID diagnosis 23.14 (21.20–25.21) 1 in 4 16.89 (15.30–18.64) 11.63 (10.02–13.42) 1 in 9 35.32 (29.95–41.64)

95% CIs provided in parentheses.

Abbreviation: ID: Intellectual Disability.

a

Adjusted for other variables considered: sex, age band, year, Townsend deprivation quintile, co-occurring ID; Adjusted rate ratios compared with the reference group for each categorical variable. Estimated with clustering at the practice level. Adjusted rate ratio for the main effect of sex: 0.33 (0.31–0.35) (male sex is reference category).