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. Author manuscript; available in PMC: 2023 Oct 1.
Published in final edited form as: Transl Stroke Res. 2022 Feb 11;13(5):830–844. doi: 10.1007/s12975-022-00994-w

Fig 5. Disruption of Sonic Hedgehog signaling affects post-stroke immature neuron migration.

Fig 5.

Newly born neuroblasts derived from SVZ dorsolateral corner migrate along the white matter tract (A, B, C, Pathway 1), while newly born neuroblasts derived from striatal side SVZ region migrate via perpendicular or parallel direction to the surface of ventricle wall into the striatum (B, C, D, Pathway 2). Quantification data showed significantly decreased migration distance via Pathway 1 (E) or Pathway 2 (F) at stroke side in Smo cKO mice (Control, n=9. Smo cKO, n=9, 2way ANOVA with Tukey’s post-hoc test). All data shown are Mean±SEM. * or # p<0.05, ** or ## p<0.01, *** or ### p<0.001. For statistical detail, see Table S1.