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. 2021 Nov 20;2(1):36–52. doi: 10.1021/acsbiomedchemau.1c00044

Figure 2.

Figure 2

Depiction of the reductive S-adenosyl-l-methionine (SAM) cleavage into 5′-deoxyadenosyl radical (5′dA·) and l-methionine (l-Met) and the substrate hydrogen abstraction catalyzed by radical SAM enzymes.