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. 2023 Apr 17;220(7):e20221649. doi: 10.1084/jem.20221649

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Figure 1. — Themis-deficient and Grb2-deficient mice exhibit a similar phenotype. (A) Phenotype of thymocytes (left panels) and splenocytes (right panels) from the indicated mice. Numbers are percentage of cells in the indicated gate. Data shown are representative of at least eight mice of each genotype. Efficient Cre-mediated deletion was confirmed in all cases where appropriate by Western blot. (B) Numbers of CD4 SP and CD8 SP thymocytes (left panels) or CD4⁺ and CD8⁺ splenocytes (right panels) from all experiments. *P < 0.05, **P < 0.01, ***P < 0.005, ****P < 0.001. T test, two tailed, Type 2. Error bars show SD.