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. 2023 Apr 17;220(7):e20221649. doi: 10.1084/jem.20221649

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Figure 3. — The developmental defect in Grb2-deficient thymocytes is rescued by deletion of Shp1 (Ptpn6) and exacerbated by overexpression of SHP1. (A and B) Phenotype of thymocytes (left panels) and splenocytes (right panels) from the indicated mice. Numbers are percentage of cells in the indicated gate. Data shown are representative of at least four mice of each genotype. Efficient Cre-mediated deletion was confirmed in all cases where appropriate by Western blot.