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. 2023 Apr 12;45(1):2199097. doi: 10.1080/0886022X.2023.2199097

Table 3.

Differences of liver function between ICU and non-ICU groups in change value and peak value.

  Not admitted to the ICU Admitted to the ICU  
Variable N = 88, mean ± SD N = 12, mean ± SD p Value
ALT (admission, U/L) 14.31 ± 7.73 24.08 ± 18.29 .05
AST (admission, U/L) 15.59 ± 8.07 29.17 ± 25.39 .06
ALP (admission, U/L) 95.59 ± 41.22 104.67 ± 38.98 .29
GGT (admission, U/L) 30.38 ± 33.92 38.17 ± 25.56 .05
TBIL (admission, μmol/L) 9.17 ± 2.35 9.70 ± 1.93 .28
DBIL (admission, μmol/L) 1.61 ± 0.80 1.88 ± 1.02 .33
INR (mean ± SD) 0.96 ± 0.11 1.03 ± 0.16 .04
ALT (peak, U/L) 17.82 ± 10.43 392.42 ± 784.15 <.01
AST (peak, U/L) 18.73 ± 10.26 986.00 ± 2115.94 <.01
ALP (peak, U/L) 102.64 ± 46.28 135.00 ± 46.21 <.01
GGT (peak, U/L) 33.95 ± 38.34 82.08 ± 45.17 <.01
TBIL (peak, μmol/L) 10.65 ± 2.91 40.10 ± 44.43 <.01
DBIL (peak, μmol/L) 2.12 ± 1.32 19.99 ± 29.40 <.01
INR (peak, μmol/L) 1.03 ± 0.25 1.42 ± 0.69 <.01
ALT (change, U/L) 3.51 ± 7.18 368.33 ± 787.33 .01
AST (change, U/L) 3.14 ± 6.63 956.83 ± 2119.87 <.01
ALP (change, U/L) 7.05 ± 16.03 30.33 ± 35.69 .01
GGT (change, U/L) 3.58 ± 8.66 43.92 ± 51.67 <.01
TBIL (change, μmol/L) 1.48 ± 2.01 30.40 ± 43.54 <.01
DBIL (change, μmol/L) 0.51 ± 0.93 18.12 ± 29.03 <.01
INR (change, μmol/L) 0.06 ± 0.17 0.39 ± 0.71 .02

Note: ICU: Intensive care unit; SD: standard deviation; ALT: Alanine aminotransferase; AST: aspartate aminotransferase; ALP: alkaline phosphatase; GGT: gamma glutamyltranspeptidase; TBIL: total bilirubin; DBIL: direct bilirubin.

The boldface represent that the p value of these variables was less than 0.05, indicating that there was a statistical difference between the two groups.