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. 2022 Sep 24;146(4):1403–1419. doi: 10.1093/brain/awac352

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© The Author(s) 2022. Published by Oxford University Press on behalf of the Guarantors of Brain.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Sufu regulates dendritic spine density. (A) Representative immunofluorescence staining images for the density and morphology of dendritic spines in Sufu knockdown neuron compared with control neuron. (B) Sufu expression in rat primary neurons was significantly knocked-down by shRNAs. (C) The result of dendritic spine density analysis for stubby, thin and mushroom spines. n = 36 for control, n = 34 for Sufu-Rat-shRNA#1, n = 40 for Sufu-Rat-shRNA#2. Unpaired two-tailed Student’s t-test; data are presented as mean ± SD.