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. 2023 Mar 27;12:e81743. doi: 10.7554/eLife.81743

Figure 8. ANDV-34 and ANDV-5 protect Syrian golden hamsters for lethal ANDV challenge.

Figure 8.

(a) Eight-week-old Syrian hamsters (n=6 per treatment group) were inoculated with 200 PFU of ANDV i.m., and 10 mg/kg of indicated mAb was administered via i.p. route at 2 and 5 dpi. Animals were treated with a dengue-specific mAb (DENV 2D22) to serve as an isotype control. (b) Kaplan-Meier survival plot. Statistical analysis of survival curves was done using a log-rank (Mantel-Cox) test comparing each group to the control (DENV 2D22), **, p=0.0014.