Extended Data Fig. 5. Comparison of WHO-based and DNA methylation-based tumor classification.

Comparison of assigned DNA methylation classes (left semicircle) and WHO-based tumor types (right semicircle) across low-grade gliomas (LGG, a), medulloblastomas (MB, b), ependymal tumors (EPN, c), embryonal/pineal tumors (EMB/PIN, d), other types (e), and samples with a descriptive diagnosis or non-neoplastic tissue (f). Colors correspond to tumor types and classes as indicated in Fig. 1 and Extended Data Fig. 1. Categories in a–f are composed by WHO-based tumor type; see Supplementary Fig. 6 for composition by DNA methylation class. See Supplementary Table 1 for underlying data.