Table 1.
Demographics, tumor characteristics and treatment details of the study cohort
| Total | OG | LG | p* | |
|---|---|---|---|---|
| n = 622 | n = 350 | n = 272 | ||
| Age, years (mean ± SD) | 68.9 ± 11.5 | 69.4 ± 11.2 | 68.2 ± 11.9 | 0.2 |
| BMI, kg/m2 (mean ± SD) | 25.8 ± 4.7 | 25.7 ± 4.8 | 25.9 ± 4.7 | 0.5 |
| Sex | 0.11 | |||
| Male | 364 (58.5) | 195 (55.7) | 169 (62.1) | |
| Female | 258 (41.5) | 155 (44.3) | 103 (37.9) | |
| ASA score | 0.7 | |||
| 1 | 165 (26.5) | 97 (27.7) | 68 (25.0) | |
| 2 | 272 (43.7) | 152 (43.4) | 120 (44.1) | |
| 3 + | 185 (29.7) | 101 (28.9) | 84 (30.9) | |
| ECOG performance status | 0.07 | |||
| 0 | 314 (50.5) | 163 (46.6) | 151 (55.5) | |
| 1 | 215 (34.6) | 133 (38.0) | 82 (30.1) | |
| 2 + | 93 (14.9) | 54 (15.4) | 39 (14.3) | |
| Clinical T category | 0.9 | |||
| T2 | 197 (31.7) | 111 (31.7) | 86 (31.6) | |
| T3 | 332 (53.4) | 189 (54.0) | 143 (52.6) | |
| T4a | 93 (15.0) | 50 (14.3) | 43 (15.8) | |
| Clinical N category | 0.4 | |||
| N0 | 433 (69.6) | 246 (70.3) | 187 (68.8) | |
| N1 | 111 (17.9) | 62 (17.7) | 49 (18.0) | |
| N2 | 58 (9.3) | 28 (8.0) | 30 (11.0) | |
| N3 | 20 (3.2) | 14 (4.0) | 6 (2.2) | |
| Clinical stage (TNM 8th edition [30]) | 0.3 | |||
| I | 172 (27.6) | 93 (26.6) | 79 (29.0) | |
| II | 286 (46.0) | 171 (48.9) | 115 (42.3) | |
| III | 164 (26.4) | 86 (24.6) | 78 (28.7) | |
| Tumor location | 0.02 | |||
| Pylorus | 91 (14.6) | 48 (13.7) | 43 (15.8) | |
| Antrum | 202 (32.5) | 98 (28.0) | 104 (38.2) | |
| Corpus | 224 (36.0) | 136 (38.9) | 88 (32.4) | |
| Fundus | 32 (5.1) | 23 (6.6) | 9 (3.3) | |
| Cardia type III | 49 (7.9) | 33 (9.4) | 16 (5.9) | |
| Unspecified or multiple locations | 24 (3.9) | 12 (3.4) | 12 (4.4) | |
| Type of gastrectomy | 0.09 | |||
| Distal | 326 (52.4) | 173 (49.4) | 153 (56.2) | |
| Total | 296 (47.6) | 177 (50.6) | 119 (43.8) | |
| Splenectomy performed | 32 (5.1) | 22 (6.3) | 10 (3.7) | 0.14 |
| Neoadjuvant treatment | 0.2 | |||
| None | 294 (47.3) | 173 (49.4) | 121 (44.5) | |
| Chemotherapy | 328 (52.7) | 177 (50.6) | 151 (55.5) | |
| Calendar year of surgery | < 0.001 | |||
| 2015 | 80 (12.9) | 58 (72.5) | 22 (27.5) | |
| 2016 | 107 (17.2) | 78 (72.9) | 29 (27.1) | |
| 2017 | 97 (15.6) | 49 (50.5) | 48 (49.5) | |
| 2018 | 123 (19.8) | 62 (50.4) | 61 (49.6) | |
| 2019 | 117 (18.8) | 52 (44.4) | 65 (55.6) | |
| 2020 | 98 (15.8) | 51 (52.0) | 47 (48.0) | |
OG open gastrectomy, LG laparoscopic gastrectomy, SD standard deviation, BMI body mass index, ASA American Society of Anesthesiologists, ECOG Eastern Cooperative Oncology Group
Data presented as n (%), unless otherwise indicated
Percentages may not add up to 100% because of rounding
*Wilcoxon rank sum test for continuous variables. Pearson’s χ2 test for categorical variables with all expected cell counts ≥ 5. Fisher’s Exact test for categorical variables with any expected cell count < 5. Significant values (p < 0.05) are indicated with bold characters