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. 2023 Apr 19;14:2233. doi: 10.1038/s41467-023-37839-5

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Unrooted ML phylogeny (LG model with empirical base frequencies, invariable sites and the discrete gamma model) of DUF4185 family sequences. Branches with greater than 75% bootstrap support (100 replicates) are highlighted in green. Units for tree scale are inferred substitutions per amino acid residue. Colored rings indicate phylum (inner) and kingdom (outer) taxonomy information for sequences. Stars highlight sequences of interest and are filled for proteins that have been experimentally characterized in this work.