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. 2023 Apr 19;13:129. doi: 10.1038/s41398-023-02412-7

Fig. 1. Conceptual framework for exploring transcriptional dynamics of MDD in the brain.

Fig. 1

Transcription dysregulation associated with depression is dynamic from predisposition to onset to illness; it is influenced by environmental exposures, contexts, and genetics, and can be studied from a variety of experimental approaches. GWAS genome-wide association study, TI transcriptomic imputation, iPSC induced pluripotent stem cells. Created with BioRender.com.