Table 3.
Fibrosis (n = 220) | Cirrhosis (n = 292) | |||||||
---|---|---|---|---|---|---|---|---|
Univariate Analysis | Multivariate Analysis | Univariate Analysis | Multivariate Analysis | |||||
OR (95% CI) | P Value | OR (95% CI) | P Value | OR (95% CI) | P Value | OR (95% CI) | P Value | |
Age (yr) | 1.031(1.009–1.054) | 0.007 | 1.018(0.983–1.054) | 0.330 | 1.030(1.009–1.053) | 0.006 | 0.987(0.949–1.028) | 0.534 |
Gender (n) | 1.063(0.619–1.826) | 0.825 | NA | 2.157(1.175–3.958) | 0.013 | 2.396(0.965–5.951) | 0.060 | |
ALT (U/L) | 0.996(0.992–1.000) | 0.052 | NA | 1.000(0.998–1.003) | 0.727 | NA | ||
AST (U/L) | 0.999(0.993–1.004) | 0.617 | NA | 1.006(1.002–1.010) | 0.007 | 0.994(0.968–1.021) | 0.682 | |
PLT (× 109/L) | 0.983(0.978–0.989) | < 0.0001 | 0.993(0.985–1.002) | 0.124 | 0.972(0.965–0.979) | < 0.0001 | 0.985(0.975–0.996) | 0.008 |
APRI score | 1.312(0.947–1.818) | 0.103 | NA | 2.120(1.604–2.802) | < 0.0001 | 0.927(0.368–2.335) | 0.872 | |
FIB-4 index | 2.373(1.625–3.465) | < 0.0001 | 1.646(1.014–2.672) | 0.044 | 1.772(1.494–2.102) | < 0.0001 | 1.533(1.019–2.306) | 0.040 |
TET3 (ng/mL) | 1.007(1.004–1.009) | < 0.0001 | 1.006(1.004–1.008) | < 0.0001 | 1.002(1.002–1.003) | < 0.0001 | 1.002(1.001–1.003) | < 0.0001 |
NA: not adopted.