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. 2023 Apr 19;13:6382. doi: 10.1038/s41598-023-33564-7

Table 3.

Univariate and multivariable analyses for liver fibrosis and cirrhosis.

Fibrosis (n = 220) Cirrhosis (n = 292)
Univariate Analysis Multivariate Analysis Univariate Analysis Multivariate Analysis
OR (95% CI) P Value OR (95% CI) P Value OR (95% CI) P Value OR (95% CI) P Value
Age (yr) 1.031(1.009–1.054) 0.007 1.018(0.983–1.054) 0.330 1.030(1.009–1.053) 0.006 0.987(0.949–1.028) 0.534
Gender (n) 1.063(0.619–1.826) 0.825 NA 2.157(1.175–3.958) 0.013 2.396(0.965–5.951) 0.060
ALT (U/L) 0.996(0.992–1.000) 0.052 NA 1.000(0.998–1.003) 0.727 NA
AST (U/L) 0.999(0.993–1.004) 0.617 NA 1.006(1.002–1.010) 0.007 0.994(0.968–1.021) 0.682
PLT (× 109/L) 0.983(0.978–0.989)  < 0.0001 0.993(0.985–1.002) 0.124 0.972(0.965–0.979)  < 0.0001 0.985(0.975–0.996) 0.008
APRI score 1.312(0.947–1.818) 0.103 NA 2.120(1.604–2.802)  < 0.0001 0.927(0.368–2.335) 0.872
FIB-4 index 2.373(1.625–3.465)  < 0.0001 1.646(1.014–2.672) 0.044 1.772(1.494–2.102)  < 0.0001 1.533(1.019–2.306) 0.040
TET3 (ng/mL) 1.007(1.004–1.009)  < 0.0001 1.006(1.004–1.008)  < 0.0001 1.002(1.002–1.003)  < 0.0001 1.002(1.001–1.003)  < 0.0001

NA: not adopted.