Table 1. Donor and Recipient Characteristics, Stratified by Recipient ADI Quintile.
| Characteristic | Recipients by ADI quintile, No. (%)a | ||||
|---|---|---|---|---|---|
| 1 (n = 6122) | 2 (n = 3742) | 3 (n = 3588) | 4 (n = 3251) | 5 (n = 2801) | |
| Candidate age at listing, median (IQR), y | 62 (52-67) | 61 (53-66) | 60 (51-65) | 59 (51-65) | 58 (49-64) |
| Race and ethnicity | |||||
| American Indian or Alaska Native | 11 (0.2) | 11 (0.3) | 5 (0.1) | 11 (0.3) | 25 (0.9) |
| Asian or Pacific Islander | 236 (3.9) | 83 (2.2) | 46 (1.3) | 43 (1.3) | 34 (1.2) |
| Hispanic | 370 (6.0) | 236 (6.3) | 304 (8.5) | 299 (9.2) | 507 (18.1) |
| Multiracial | 17 (0.3) | 4 (0.1) | 10 (0.3) | 7 (0.2) | 9 (0.3) |
| Non-Hispanic Black | 321 (5.2) | 274 (7.3) | 301 (8.4) | 339 (10.4) | 626 (22.3) |
| Non-Hispanic White | 5167 (84.4) | 3134 (83.8) | 2922 (81.4) | 2552 (78.5) | 1600 (57.1) |
| Diagnosisb | |||||
| A | 1206 (19.7) | 974 (26.0) | 1009 (28.1) | 956 (29.4) | 738 (26.3) |
| B | 270 (4.4) | 159 (4.2) | 146 (4.1) | 140 (4.3) | 147 (5.2) |
| C | 612 (10) | 345 (9.2) | 333 (9.3) | 304 (9.4) | 214 (7.6) |
| D | 4034 (65.9) | 2264 (60.5) | 2100 (58.5) | 1851 (56.9) | 1702 (60.8) |
| Blood type | |||||
| A | 2429 (39.7) | 1501 (40.1) | 1433 (39.9) | 1271 (39.1) | 1022 (36.5) |
| AB | 256 (4.2) | 169 (4.5) | 148 (4.1) | 104 (3.2) | 98 (3.5) |
| B | 688 (11.2) | 413 (11.0) | 401 (11.2) | 363 (11.2) | 324 (11.6) |
| O | 2749 (44.9) | 1659 (44.3) | 1606 (44.8) | 1513 (46.5) | 1357 (48.4) |
| BMI, median (IQR) | 25.6 (21.8-29.1) | 26.3 (22.3-29.3) | 26.1 (22.1-29.2) | 26.0 (22.1-29.2) | 26.2 (22.4-29.5) |
| Unknown | 3 | 1 | 1 | 1 | 3 |
| Functional status | |||||
| No assistance | 695 (11.4) | 268 (7.2) | 265 (7.4) | 226 (7) | 176 (6.3) |
| Some assistance | 4975 (81.3) | 3182 (85) | 3050 (85) | 2756 (84.8) | 2360 (84.3) |
| Full assistance | 438 (7.2) | 283 (7.6) | 266 (7.4) | 254 (7.8) | 250 (8.9) |
| Unknown | 14 | 9 | 7 | 15 | 15 |
| Six-min walk distance, median (IQR), m | 850 (500-1128) | 843 (535-1100) | 850 (525-1110) | 820 (492-1100) | 800 (456-1070) |
| Unknown | 114 | 68 | 57 | 73 | 49 |
| Cardiac Index, median (IQR) | 2.80 (2.40-3.30) | 2.78 (2.40-3.20) | 2.80 (2.41-3.26) | 2.80 (2.40-3.28) | 2.80 (2.40-3.32) |
| Unknown | 1584 | 963 | 924 | 836 | 754 |
| Bilirubin, median (IQR), mg/dL | 0.50 (0.30-0.70) | 0.50 (0.30-0.60) | 0.45 (0.30-0.70) | 0.50 (0.30-0.60) | 0.40 (0.30-0.60) |
| Unknown | 1879 | 1192 | 1080 | 1034 | 794 |
| Creatinine, median (IQR), mg/dL | 0.80 (0.69-0.97) | 0.80 (0.69-1.00) | 0.80 (0.69-0.96) | 0.80 (0.68-0.97) | 0.80 (0.67-0.96) |
| Unknown | 24 | 15 | 18 | 11 | 17 |
| Supplemental oxygen, median (IQR), L | 4.0 (3.0-6.0) | 4.0 (3.0-6.0) | 4.0 (3.0-6.0) | 4.0 (2.5-6.0) | 4.0 (3.0-6.0) |
| Unknown | 801 | 505 | 497 | 453 | 410 |
| Respiratory support | |||||
| BiPAP | 390 (6.4) | 240 (6.4) | 276 (7.7) | 276 (8.5) | 214 (7.6) |
| Mechanical | 353 (5.8) | 203 (5.4) | 194 (5.4) | 183 (5.6) | 167 (6) |
| None | 5014 (81.9) | 3070 (82.0) | 2913 (81.2) | 2611 (80.3) | 2262 (80.8) |
| CPAP | 356 (5.8) | 222 (5.9) | 199 (5.5) | 175 (5.4) | 153 (5.5) |
| Unknown | 9 | 7 | 6 | 6 | 5 |
| Pco2, median (IQR), mm Hg | 44 (38-51) | 44 (39-52) | 45 (39-53) | 45 (39-53) | 45 (39-52) |
| Unknown | 260 | 169 | 172 | 131 | 117 |
| Supplemental oxygen, median (IQR), % | 100 (56-100) | 90 (57-100) | 80 (52-100) | 84 (60-100) | 90 (52-100) |
| Unknown | 5495 | 3330 | 3194 | 2867 | 2471 |
| Pulmonary artery systolic pressure, median (IQR), mm Hg | 38 (31-48) | 39 (32-49) | 39 (32-48) | 39 (32-49) | 40 (33-50) |
| Unknown | 1382 | 807 | 785 | 719 | 643 |
| Donor age, median (IQR), y | 33 (23-47) | 33 (23-47) | 33 (23-46) | 33 (23-46) | 32 (22-46) |
| Donor race | |||||
| American Indian or Alaska Native | 33 (0.5) | 14 (0.4) | 16 (0.4) | 20 (0.6) | 16 (0.6) |
| Asian or Pacific Islander | 209 (3.4) | 140 (3.7) | 108 (3.0) | 102 (3.1) | 76 (2.7) |
| Hispanic | 1078 (17.6) | 547 (14.6) | 556 (15.5) | 476 (14.6) | 460 (16.4) |
| Multiracial | 23 (0.4) | 11 (0.3) | 6 (0.2) | 5 (0.2) | 6 (0.2) |
| Non-Hispanic Black | 1093 (17.9) | 659 (17.6) | 710 (19.8) | 628 (19.3) | 577 (20.6) |
| Non-Hispanic White | 3686 (60.2) | 2371 (63.4) | 2192 (61.1) | 2020 (62.1) | 1666 (59.5) |
| Donor ADI quintile | |||||
| 1 | 1485 (24.3) | 828 (22.1) | 688 (19.2) | 632 (19.4) | 545 (19.5) |
| 2 | 1015 (16.6) | 660 (17.6) | 611 (17) | 544 (16.7) | 425 (15.2) |
| 3 | 1050 (17.2) | 705 (18.8) | 665 (18.5) | 591 (18.2) | 495 (17.7) |
| 4 | 1141 (18.6) | 707 (18.9) | 762 (21.2) | 683 (21.0) | 575 (20.5) |
| 5 | 1431 (23.4) | 842 (22.5) | 862 (24) | 801 (24.6) | 761 (27.2) |
Abbreviations: ADI, area deprivation index; BiPAP, bilevel positive airway pressure; BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); CPAP, continuous positive airway pressure; Pco2, partial pressure of carbon dioxide.
SI conversion factors: To convert bilirubin to micromoles per liter, multiply by 17.104; creatinine to micromoles per liter, multiply by 88.4.
a
ADI quintile 1 indicates most resourced and 5, least resourced.
b
Diagnosis group A indicates obstructive lung disease; group B, pulmonary vascular disease; group C, cystic fibrosis and immunodeficiency disorders; and group D, restrictive lung diseases.