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. 2023 Apr 6;11:1063250. doi: 10.3389/fpubh.2023.1063250

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Copyright © 2023 Roggan, Kronenberg, Wollert, Hoffmann, Nisar, Konda, Diegeler, Liemersdorf and Hellweg.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Gene expression of astrocytes 24 h after exposure to 2 Gy X-rays. Gene expression of primary murine astrocytes was analyzed using RNA sequencing (n = 4). (A) In this volcano plot, the log₁₀ of the adjusted P-value [log₁₀ (padj)] is plotted against the log₂ Fold Change in expression of each gene. The two upregulated genes (pink dots) are annotated as well as some of the most significantly downregulated genes (green dots). (B) Gene ontology (GO) terms that were significantly enriched with an adjusted P-value < 0.05 in the differentially expressed gene sets are listed (up to 40 terms). The full list of enriched GO terms is available in Supplementary material.