Table 2.
Bivariate Association Between Prescription of World Health Organization–Recommended Antibiotics and Development of Persistent Diarrhea (≥14-Day Duration)
| Children With MSD, No. (%)a | ||||
|---|---|---|---|---|
| Diarrhea Type by Antibiotic Prescription Status | Total | Not Persistent | Persistent | P Value |
| Any diarrhea | n = 4560 | n = 4124 | n = 436 | |
| ȃNo antibiotics prescribed | 3678 (80.4) | 3307 (80.2) | 371 (85.1) | .01b |
| ȃAntibiotics prescribed | 882 (19.6) | 817 (19.8) | 65 (14.9) | |
| Acute bloody diarrhea | n = 697 | n = 631 | n = 66 | |
| ȃNo antibiotics prescribed | 263 (37.7) | 234 (37.1) | 29 (43.9) | .27 |
| ȃAntibiotics prescribed | 434 (62.3) | 397 (62.9) | 37 (56.1) | |
| Acute watery diarrhea | n = 3863 | n = 3493 | n = 370 | |
| ȃNo antibiotics prescribed | 3415 (88.4) | 3073 (88) | 342 (92.4) | .01b |
| ȃAntibiotics prescribed | 448 (11.6) | 420 (12) | 28 (7.6) | |
Abbreviation: MSD, moderate-to-severe diarrhea.
Including all children with MSD for whom prescribing information was available.
Significant at P < .05 (P values based on χ2 test).