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. 2023 Apr 19;12:37. doi: 10.1186/s13756-023-01238-8

Table 2.

Fixed-dose combination antibiotics on the Tanzanian 2021 National Essential Medicines List (NEMLIT) [22]

Drug combination Fixed dose combinations1 Tanzania EML
AWaRe classification and level of allowed prescription2
WHO AWaRe classification3
Not listed on the WHO essential medicine list (EML)
ampicillin-cloxacillin

Caps 250/250 mg

Inj 250/250 mg

Access (B) Not Recommended
flucloxacillin-amoxicillin Table 250/250 mg Access (C) Not Recommended
ceftriaxone-sulbactam Inj 1000/500 mg Watch (D) Not Recommended
ampicillin-sulbactam

Inj 1000/500 mg

Inj 2000/1000 mg

Inj 10.000/5000 mg

Watch (C) Access (but not listed on the WHO EML)
Listed on the WHO essential medicine list (EML)
amoxicillin-clavulanic acid

Susp 125/31,25 mg

Susp 250/62,5 mg

Table 500/125 mg

Access (B) Access (EML)
Inj 500/100 mg Access (C)
piperacillin-tazobactam

Inj 2000/250 mg

Inj 4000/500 mg

Watch (S) Watch (EML)
sulfamethoxazole- trimethoprim

Susp 200/40 mg

Table 400/80 mg

Watch (A) Access (EML)

Note: Combinations of antimicrobials intended for treatment or prophylaxis of tuberculosis, malaria or viral infections are not included in this overview1. Abbreviations : Caps = capsule, Inj = powder for injection, Susp = power for suspension (dose per 5 mL), Tab = tablet. Tanzania AWaRe classification and level of prescription2: assessed using the Tanzanian 2021 guidelines (21). Level of prescription indicates if there is a restriction with regard to service provision or professional expertise. It indicates the lowest level for which prescription is allowed. B: health centre/clinical officer, C: district hospital/assistant medical officer, D: regional referral hospital/ medical officer, S: tertiary hospital/specialist. WHO EML 2021 AWaRe classification3: assessed using the online database (12) (https://aware.essentialmeds.org/list) and the Excel database document (11) (https://www.who.int/publications/i/item/2021-aware-classification)