Table 2.
Fixed-dose combination antibiotics on the Tanzanian 2021 National Essential Medicines List (NEMLIT) [22]
| Drug combination | Fixed dose combinations1 | Tanzania EML AWaRe classification and level of allowed prescription2 |
WHO AWaRe classification3 |
|---|---|---|---|
| Not listed on the WHO essential medicine list (EML) | |||
| ampicillin-cloxacillin |
Caps 250/250 mg Inj 250/250 mg |
Access (B) | Not Recommended |
| flucloxacillin-amoxicillin | Table 250/250 mg | Access (C) | Not Recommended |
| ceftriaxone-sulbactam | Inj 1000/500 mg | Watch (D) | Not Recommended |
| ampicillin-sulbactam |
Inj 1000/500 mg Inj 2000/1000 mg Inj 10.000/5000 mg |
Watch (C) | Access (but not listed on the WHO EML) |
| Listed on the WHO essential medicine list (EML) | |||
| amoxicillin-clavulanic acid |
Susp 125/31,25 mg Susp 250/62,5 mg Table 500/125 mg |
Access (B) | Access (EML) |
| Inj 500/100 mg | Access (C) | ||
| piperacillin-tazobactam |
Inj 2000/250 mg Inj 4000/500 mg |
Watch (S) | Watch (EML) |
| sulfamethoxazole- trimethoprim |
Susp 200/40 mg Table 400/80 mg |
Watch (A) | Access (EML) |
Note: Combinations of antimicrobials intended for treatment or prophylaxis of tuberculosis, malaria or viral infections are not included in this overview1. Abbreviations : Caps = capsule, Inj = powder for injection, Susp = power for suspension (dose per 5 mL), Tab = tablet. Tanzania AWaRe classification and level of prescription2: assessed using the Tanzanian 2021 guidelines (21). Level of prescription indicates if there is a restriction with regard to service provision or professional expertise. It indicates the lowest level for which prescription is allowed. B: health centre/clinical officer, C: district hospital/assistant medical officer, D: regional referral hospital/ medical officer, S: tertiary hospital/specialist. WHO EML 2021 AWaRe classification3: assessed using the online database (12) (https://aware.essentialmeds.org/list) and the Excel database document (11) (https://www.who.int/publications/i/item/2021-aware-classification)