Table 1.

Patients’ baseline characteristics and outcomes

Demographic characteristics
Male : female	4 : 10
Age (years): median (range)	23 (4 – 38)
Comorbidities
Malaria: n/N (%) patients tested	11/13 (85%)
HIV: n/N (%) patients tested	1/3 (7%)
General characteristics
Time (days) from symptom onset to treatment start: median (range)	21 (5–45)
Signs and symptoms: n/N (%) patients
Fever (temperature >38·0 °C)	9/14 (64%)
Patients with lesions:	14/14 (100%)
Patients with new lesions	10/14 (71%)
Number of patients with >100 lesions	11/14 (79%)
Outcome: n/N (%) patients
Completed full course of treatment	14/14 (100%)
PCR positive at day 4	7/14 (50%)
PCR positive at day 8	1/10 (10%)
PCR positive at day 14	1/8 (12%)
PCR positive at day 21	1/2 (50%)
PCR positive at final visit	1/13 (8%)
Time (days) to no new lesions: median (range)	5 (0–28)
Recovered without sequelae at D28	4/13 (31%)
Recovered with sequelae at D28	9/13 (69%)
Patients with at least one serious adverse event	2/14 (14%)