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. Author manuscript; available in PMC: 2023 Sep 12.
Published in final edited form as: Curr Biol. 2022 Jul 26;32(17):3704–3719.e7. doi: 10.1016/j.cub.2022.07.003

Figure 7. Effects of EGFR signaling on ISC gene expression and metabolism.

Figure 7.

We show the effects of upregulating EGFR signaling in the ISC nucleus (blue), mitochondrion (yellow), and cytoplasm (grey). Green arrows indicate example processes, gene products, and metabolites that are up-regulated by EGFR signaling in response to the EGFR-dependent transcription factors Cic, Pnt and Ets21C.