Table 7.
Accuracy of specific signs and symptoms for predicting clinicopathologically defined PSP (using >1 as cutoff) (any exam)
| Path PSP | Path non-PSP | Sensitivity | Specificity | PPV | NPV | Accuracy | |
|---|---|---|---|---|---|---|---|
| UPDRS II fall score (any exam > 1) | |||||||
| Yes | 31 | 126 | 36.9% (26.6%, 48.1%) | 19.7% | 93.0% | 80.3% | |
| No | 53 | 701 | 84.8% (82.1%, 87.1%) | ||||
| UPDRS II swallow score (any exam > 1) | |||||||
| Yes | 29 | 147 | 34.1% (24.2%, 45.2%) | 16.5% | 92.4% | 77.7% | |
| No | 56 | 681 | 82.2% (79.4%, 84.8%) | ||||
| UPDRS II freeze score (any exam > 1) | |||||||
| Yes | 22 | 124 | 26.2% (17.2%, 36.9%) | 15.1% | 91.9% | 79.6% | |
| No | 62 | 704 | 85.0% (82.4%, 87.4%) | ||||
| UPDRS III speech motor score (any exam > 1) | |||||||
| Yes | 48 | 253 | 55.8% (44.7%, 66.5%) | 15.9% | 93.7% | 67.8% | |
| No | 38 | 565 | 69.1% (65.8%, 72.2%) | ||||
| UPDRS III facial expression score (any exam > 1) | |||||||
| Yes | 46 | 252 | 53.5% (42.4%, 64.3%) | 15.4% | 93.4% | 67.7% | |
| No | 40 | 566 | 69.2% (65.9%, 72.3%) | ||||
| UPDRS III posture stability score (any exam > 1) | |||||||
| Yes | 69 | 578 | 80.2% (70.2%, 88.0%) | 10.7% | 93.3% | 33.9% | |
| No | 17 | 236 | 29.0% (25.9%, 32.3%) | ||||