Table 8.
Odds ratios for the association of diagnoses or symptoms and prediction of clinicopathologically defined PSP
| Univariate model |
Multivariable model |
|||||
|---|---|---|---|---|---|---|
| Predictor | Level | Path PSP N, total N | Odds ratio (95% CI) | p-Value | Odds ratio (95% CI) | p-Value |
| PSP diagnosis at any movement Dx | No | 69 (7.6%), 912 | 1 | |||
| Yes | 18 (66.7%), 27 | 24.43 (10.58, 56.43) | <0.001 | |||
| PSP at first movement Dx | No | 79 (8.5%), 928 | 1 | |||
| Yes | 8 (72.7%), 11 | 28.64 (7.45, 110.09) | <0.001 | |||
| PSP at Last movement Dx | No | 73 (7.9%), 919 | 1 | |||
| Yes | 14 (70.0%), 20 | 27.02 (10.08, 72.41) | <0.001 | |||
| PSP at final movement Dx | No | 69 (7.5%), 915 | 1 | |||
| Yes | 18 (75.0%), 24 | 36.78 (14.14, 95.68) | <0.001 | |||
| UPDRS II fall score (any exam > 1) | No | 53 (7.0%), 753 | 1 | 1 | ||
| Yes | 31 (19.7%), 157 | 3.25 (2.01, 5.26) | <0.001 | 2.11 (1.21, 3.68) | 0.009 | |
| UPDRS II swallow score (any exam > 1) | No | 56 (7.6%), 736 | 1 | |||
| Yes | 29 (16.5%), 176 | 2.40 (1.48, 3.88) | <0.001 | |||
| UPDRS II freeze score (any exam > 1) | No | 62 (8.1%), 765 | 1 | |||
| Yes | 22 (15.1%), 146 | 2.01 (1.19, 3.39) | 0.009 | |||
| UPDRS III speech motor score (any exam > 1) | No | 38 (6.3%), 602 | 1 | 1 | ||
| Yes | 48 (15.9%), 301 | 2.82 (1.79, 4.42) | <0.001 | 1.72 (1.02, 2.91) | 0.042 | |
| UPDRS III facial expression score (any exam > 1) | No | 40 (6.6%), 605 | 1 | |||
| Yes | 46 (15.4%), 298 | 2.58 (1.65, 4.04) | <0.001 | |||
| UPDRS III posture stability score (any exam > 1) | No | 17 (6.7%), 253 | 1 | |||
| Yes | 69 (10.7%), 646 | 1.66 (0.96, 2.88) | 0.072 | |||
| Downgaze palsy | No | 71 (7.9%), 896 | 1 | |||
| Yes | 16 (44.4%), 36 | 9.30 (4.62, 18.74) | <0.001 | |||
| Square wave jerks | No | 74 (8.2%), 906 | 1 | 1 | ||
| Yes | 13 (48.1%), 27 | 10.44 (4.73, 23.04) | <0.001 | 5.99 (2.51, 14.34) | <0.001 | |
| RBD diagnosis | Yes | 10 (9.6%), 104 | 1 | |||
| No | 61 (9.2%), 666 | 0.95 (0.47, 1.91) | 0.881 | |||