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. Author manuscript; available in PMC: 2023 Jul 11.
Published in final edited form as: Sci Transl Med. 2023 Jan 11;15(678):eadd8469. doi: 10.1126/scitranslmed.add8469

Figure 6. Panel autoantibodies can accurately detect SCLC.

Figure 6.

(A) Panel autoantibodies were analyzed as a function of the time of blood draw in the CHS cohort (pre-diagnostic, 1 to 2 years prior to diagnosis (dx) or less than 1 year to dx) and Fred Hutch or Vanderbilt cohorts (diagnostic, limited or extensive stage); *p<0.05; **p<0.005, ***p<0.0005 unpaired t-test. (B) Panel autoantibodies are significantly higher in plasma from SCLC cases (n=98) compared to cases from other cancers (n=75 NSCLC, n=86 pancreatic, n=87 colon) or controls (n=175) from all cohorts **p<0.001 unpaired t-test. Data are presented as individual data points, the horizonal bar as mean ± SEM.