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. 2023 Apr 20;3(4):672–683. doi: 10.1158/2767-9764.CRC-23-0015

FIGURE 5.

FIGURE 5

High LRG1 expression is associated with distant metastasis in patients that do not respond to neoadjuvant ipilimumab and nivolumab. LRG1 expression measured in patient plasma by MS for patients without a response upon neoadjuvant ICB of the OpACIN-neo study (n = 20; A) and PRADO study (n = 11; B). Comparing patients without a recurrence (green), patients with a local recurrence (pink) and patients with a distant recurrence (red). A two-tailed unpaired Student t test for comparing patient groups. *, P < 0.05.