. 2023 Feb 20;180(6):786–788. doi: 10.1111/bph.16031

TABLE 1.

The correct Ishihara model

I_K1 = G_K1 · (V − E_K) · (phi·f_O·y₁ + [1 − phi] · y₂)

G_K1 = 2.5 · ([K⁺]_o/5.4)^0.4

High‐affinity channel

α = 0.17·exp(−0.07 · ((V − E_K) + 8·[Mg²⁺]_i))

/ (1 + 0.01·exp(0.12 · ( (V − E_K) + 8·[Mg²⁺]_i) ) )

β = [SPM]_i·280·exp(0.15 · ( (V − E_K) + 8·[Mg²⁺]_i) )

/ (1 + 0.01·exp(0.13 · ( (V − E_K) + 8·[Mg²⁺]_i) ) )

K_dMg = 0.45·exp(−(V − E_K) /20)

f_O = 1/ (1 + [Mg²⁺]_i/K_dMg)

dy₁/dt = α · (1 − y₁) – β · (f_O)³ · y1

Low‐affinity channel

K_{dSPM_L} = 0.04·exp(−(V − E_K) /9.1)

y2 = 1/ (1 + [SPM]_i/K_{dSPM_L})

Note: The bolded red parentheses were incorrectly omitted from the dynamic clamp implementation.