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. Author manuscript; available in PMC: 2023 Apr 20.
Published in final edited form as: J Alzheimers Dis. 2022;89(2):641–658. doi: 10.3233/JAD-215728

Table 3.

Results of logistic regression comparing each NPI symptom across patient groups (bvAD, bvFTD, aAD)

Neuropsychiatrie Inventory bvAD bvFTD aAD bvFTD versus bvAD aAD versus bvAD
Presence of Symptoms n = 13 n = 58 n=14 β SE z p β SE z p
Delusions n with symptom (% of total) 5 (38%) 14 (24%) 0 (0%) −0.63 0.72 −0.87 0.38 −18.1 1723 −0.01 0.99
Hallucinations n with symptom (% of total) 2 (15%) 7 (12%) 1 (7%) −0.23 0.94 −0.25 0.81 −0.88 1.29 −0.68 0.5
Agitation/Aggression n with symptom (% of total) 12 (92%) 33 (57%) 8 (57%) −2.38 1.12 −2.13 0.03* −2.23 1.18 −1.89 0.06
Depression/Dysphoria n with symptom (% of total) 7 (54%) 26 (45%) 5 (36%) −0.54 0.67 −0.81 0.42 −0.73 0.79 −0.93 0.35
Anxiety n with symptom (% of total) 8 (62%) 33 (57%) 7 (50%) −0.12 0.67 −0.18 0.86 −0.47 0.78 −0.61 0.55
Euphoria/Elation n with symptom (% of total) 5 (38%) 29 (50%) 4 (29%) 0.56 0.68 0.82 0.41 −0.48 0.83 −0.58 0.57
Apathy n with symptom (% of total) 11 (85%) 51 (88%) 9 (64%) 0.05 0.93 0.05 0.96 −1.12 0.95 −1.17 0.24
Disinhibition n with symptom (% of total) 10 (77%) 44 (76%) 3 (21%) −0.37 0.79 −0.46 0.64 −2.56 0.94 −2.72 0.006**
Irritability/Emotional Lability n with symptom (% of total) 11 (85%) 34 (59%) 8 (57%) −1.29 0.85 −1.52 0.13 −1.42 0.94 −1.51 0.13
Motor Disturbance n with symptom (% of total) 9 (69%) 35 (60%) 3 (21%) −1.01 0.76 −1.32 0.19 −2.38 0.96 −2.47 0.01*
Nighttime Behaviors n with symptom (% of total) 6 (46%) 30 (52%) 4 (29%) 0.39 0.66 0.59 0.56 −0.78 0.81 −0.95 0.34
Appetite n with symptom (% of total) 8 (62%) 39 (67%) 8 (57%) 0.03 0.68 0.04 0.97 −0.17 0.79 −0.22 0.83
n = 13 n = 57 n=13 F p F p
NPI Total M 12 9 4 0.24 0.63 10.41 0.004**
Severity of Symptoms IQI 8–16 6–15 2–8

Beta estimate (β), standard error (SE), z-value (z), and p-value (p) are relative to bvAD performance. Asterisks indicate difference from bvAD:

*

p < 0.05,

**

p< 0.01.