Figure 4.

Circular genome representation of five novel bacteriophages isolated from human skin. For each panel, the inner ring illustrates the GC skew. The second ring shows putative coding sequences; the color of each arrow indicates predicted function. The remaining outer rings illustrate BLASTn sequence similarities for comparisons with other staphylococcal bacteriophages. vB_SepS_BE01 shows sequence similarity with phages of the Phietavirus genus (A), and vB_SepS_BE02 is similar to phages of the Sextaecvirus genus (B). vB_SepP_BE03 is a podovirus (C). An asterisk is included to highlight a sequence predicted to code for an N-acetylmuramoyl-L-alanine amidase (see Figure S1, Supporting Information). The final two phages, vB_SepM_BE04 (D) and vB_SepM_BE06 (E), are similar to known myoviruses of the Sepunavirus genus. Plots were generated using the CGView server (Grant and Stothard 2008).