Table 1.
Putative potassium transporters in S. venezuelae. Candidates for potassium uptake and/or export were identified using TransportDB database (Elbourne et al. 2017) and the BLAST function in StrepDB (https://strepdb.streptomyces.org.uk/). None of the listed proteins has been characterized experimentally prior publication of this review. Relevant domains were identified using InterPro (https://www.ebi.ac.uk/interpro/). Number of transmembrane domains (TM) was predicted using uniprot (https://www.uniprot.org/). For details see text.
| vnz number (StrepDB) | sven number (StrepDB) |
Name | Predicted domain architecture | Family |
|---|---|---|---|---|
| Vnz_12290 | Sven2511 | KdpF | 1 TM helix | K+-transporting ATPase, subunit F |
| Vnz_12285 | Sven2510 | KdpA | 10 TM helices | K+-transporting ATPase, subunit A |
| Vnz_12280 | Sven2509 | KdpB | 7 TM helices P-type ATPase, cytoplasmic domain N (IPR023299); P-type ATPase, phosphorylation site (IPR018303); P-type ATPase, A domain superfamily (IPR008250) |
K+-transporting ATPase, subunit B |
| Vnz_12275 | Sven2508 | KdpC | 1 TM helix | K+-transporting ATPase, subunit C |
| Vnz_27465 | Sven5551 | 12 TM helices Amino acid/polyamine transporter I (IPR002293) |
Conserved membrane protein (39% identity to KimA from B. subtilis) |
|
| Vnz_15480 | Sven3148 | 12 TM helices Amino acid/polyamine transporter I (IPR002293) |
Conserved membrane protein (42% identity to KimA from B. subtilis) |
|
| Vnz_28525 | Sven5767 | 13 TM helices Cation/H+ exchanger (IPR006153) |
Putative transmembrane transport protein (34% identity to KhtU from B. subtilis) |
|
| Vnz_28050 | Sven5672 | CpeB | 13 TM helices Cation/H+ exchanger (IPR006153) |
Putative transmembrane transport protein (32% identity to KhtU from B. subtilis) |
| Vnz_17705 | Sven3600 | 2 TM helices Potassium channel domain (IPR013099) NAD(P)-binding domain superfamily (IPR036291) Regulator of K+ conductance, N-terminal (IPR003148) |
Potassium channel protein (24% identity to the Ca2+ gated potassium channel MthK from M. thermautotrophicus) |
|
| Vnz_00420 | Sven0095 | 3 TM helices Potassium channel domain (IPR013099) |
Potassium channel protein | |
| Vnz_05495 | Sven1132 | 4 TM helices Potassium channel domain (IPR013099) Voltage-gated potassium channel (IPR028325) |
Potassium voltage-gated channel subfamily KQT | |
| Vnz_10685 | Sven2186 | 2 TM helices Potassium channel domain (IPR013099) Voltage-gated potassium channel (IPR028325) |
Potassium voltage-gated channel subfamily KQT |