Table 2.

Chi-square Test for the Hypothesis of Homogeneous Distribution of Us at First, Second, and Third Codon Positions.

	Kinetoplastids				Diplonemids		Euglenid	Jakobids
mRNA	T. brucei	L. tarentolae	C. fasciculata	A. deanei	D. ambulator	L. lanifica	E. gracilis	J. libera	R. americana
COX1	0.0015	0.0028	0.0059	3.35 × 10−5	2 × 10−9	3 × 10−9	1 × 10−7	8.7 × 10−8	8 × 10−7
COX2	0.26	0.81	0.64	0.47	8 × 10−4	0.0011	0.0012	1.7 × 10−8	4 × 10−5
COX3 a	0.18	0.67	0.36	0.84	5 × 10−6	1 × 10−8	0.0028	7 × 10−4	0.0023
NAD1	0.0097	0.002	2 × 10−4	7 × 10−5	2 × 10−5	1 × 10−5	0.48	0.016	0.006
NAD5	0.036	0.53	0.83	0.23	0.0045	1 × 10−6	na	0.0026	9 × 10−8
NAD7 a	0.11	0.92	0.43	0.95	4 × 10−7	4 × 10−8	na	1 × 10−7	1 × 10−4
NAD9 b	0.44	0.85	na	na	0.017	na	na	0.036	3 × 10−4
ATP6 a	0.36	0.61	0.66	0.92	0.017	1 × 10−5	na	0.033	0.024
RPS12 b	0.46	0.39	0.15	na	na	na	0.65	6 × 10−4	0.001

Note.—The values indicate the P value for a chi-square test with a null hypothesis of a homogeneous distribution of Us at the first, second, and third codon positions. Bold values indicate P < 0.05 discarding the hypothesis of homogeneous distribution of the U content in different codon positions showing preference for certain codon position. Note that pan-edited mRNAs have nonstatistically significant P values in kinetoplastids. na, not available.

^aPan-edited in T. brucei and partially edited in other kinetoplastids.

^bPan-edited in the analyzed kinetoplastids.