Table 1.
All patients | Tertile 1 | Tertile 2 | Tertile 3 | P value | |
---|---|---|---|---|---|
(n = 56) | (n = 19) | (n = 19) | (n = 18) | ||
Clinical | |||||
Age, yr | 64 ± 8 | 64 ± 8 | 62 ± 7 | 65 ± 9 | .513 |
Male, n (%) | 38 (68) | 13 (69) | 12 (58) | 14 (78) | .629 |
BMI, kg/m2 | 28 ± 5 | 30 ± 4 | 27 ± 4 | 28 ± 6 | .148 |
Diabetes mellitus, n (%) | 30 (54) | 3 (27.3) | 15 (62.5) | 11 (52.4) | .003 |
Hypertension, n (%) | 31 (55) | 9 (47) | 12 (63) | 10 (56) | .619 |
Current - previous smoking, n (%) | 32 (57) | 13 (68) | 10 (53) | 12 (67) | .546 |
Laboratory | |||||
CRP, mg/L (M, IQ) | 3.77 (1.80–7.04) | 4.27 (2.29–7.09) | 2.04 (1.41–5.32) | 5.58 (2.58–13.54) | >.05 |
CK, U/L (M, IQ) | 94,5 (74.5–176.3) | 95 (76.5–136.5) | 95 (75–152.5) | 91.5 (67.5–119.3) | >.05 |
CKMB, U/L (M, IQ) | 1.27 (0.72–1.73) | 1.41 (0.69–1.80) | 1.24 (0.9–1.66) | 1.27 (0.74–1.79) | >.05 |
Hematocrit, % (M, IQ) | 43 (40–46,25) | 45.0 (40.5–47) | 42.0 (40.0–45.5) | 42.5 (41.0–45.0) | >.05 |
Cr, mg/dL (M, IQ) | 1.0 (0.89–1.10) | 0.97 (0.91–1.07) | 1.00 (0.83–1.08) | 1.03 (0.91–1,18) | >.05 |
CMR | |||||
Septum, mm | 9.5 ± 1.7 | 9.1 ± 1.2 | 9.6 ± 1.8 | 9.5 ± 1.8 | .607 |
LA, mm | 34 ± 5 | 33 ± 5 | 35 ± 4 | 36 ± 6 | .191 |
LVEDV index, ml/m2 | 67 ± 20 | 65 ± 21 | 63 ± 12 | 72 ± 24 | .357 |
LVESV index, ml/m2 | 23 ± 11 | 23 ± 13 | 21 ± 6 | 25 ± 12 | .537 |
LVEF, % | 66 ± 8 | 67 ± 9 | 67 ± 6 | 65 ± 9 | .691 |
LV mass index, ml/m2 | 63 ± 16 | 59 ± 10 | 61 ± 17 | 70 ± 16 | .062 |
Native T1, ms | 1019 ± 32 | 1006 ± 27 | 1016 ± 27 | 1034 ± 37 | .025 |
Contrast T1, ms | 479 ± 47 | 472 ± 41 | 475 ± 44 | 492 ± 57 | .397 |
ECV, % | 24 ± 3 | 22 ± 2 | 23 ± 1.9 | 25 ± 3 | .001 |
BMI = body mass index, CCS = Canadian Cardiovascular Society, CMR = cardiovascular magnetic resonance, ECV = extracellular volume fraction, eGFR = estimated glomerular filtration rate, LA = left atrium, LV = left ventricle, LVEDV = Left ventricular end–diastolic volume, LVESV = Left ventricular end systolic volume.