Table 1. Descriptive statistics of 24 cases of patients that developed Graves disease after Hashimoto Thyroiditis.
| Hashimoto Thyroiditis hypothyroidism | Graves hyperthyroidism | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Mean | SD | Median | Range | Mean | SD | Median | Range | p | |
| Age at diagnosis (years) | 39 | 13 | 39 | 18 | 42 | 11.3 | 42 | 45 | ns |
| Levothyroxine dose (µg/day) | 66 | 30 | 58.7 | 125 | na | na | na | na | na |
| Thyroid volume (mL) | 7.4 | 3.1 | 7.2 | 12.3 | 7.38 | 3.1 | 5.2 | 12 | ns |
| TSH (mUI/L) | 9.4 | 26.1 | 3 | 12.2 | < 0.01 | - | < 0.01 | - | < 0.05 |
| FT3 (pmol/L) | 3.6 | 1.8 | 4.7 | 12 | 7.9 | 8.8 | 24 | < 0.05 | |
| FT4 (pmol/L) | 8.7 | 5.1 | 10.5 | 13.5 | 34 | 32 | 24.5 | 31 | < 0.05 |
| Anti TPO antibodies (IU/mL) | 383 | 988 | 146 | 4735 | 335 | 240 | 273 | 580 | ns |
| TBII (IU/L) | nd | nd | nd | nd | 7.9 | 7.1 | 4.8 | 13 | na |
| Switch from HT to GD (months) | na | na | na | na | 38 | 45 | 18 | 168 | na |
nd: not done; ns: non significant; na: not applicable.